Rodríguez Colorado, NancyLópez Herrera, AlbeiroEcheverri Zuluaga, José Julián2020-12-102020-12-102013Revista Lasallista de Investigación - Vol. 10 No. 2 - 20131794-4449http://hdl.handle.net/10567/2816Lactoferrin stimulates or inhibits se-veral humoral and cellular components of the im-munity. given its qualities, it can play a role in the prevention of mammary gland ́s infections. objec-tive. To explore the association of the intron 6 po-lymorphism of the bovine lactoferrin gene with milk production, fat and protein percentages and somatic cells count in a population of Holstein cows, in Antio-quia. Materials and methods. This research work was performed with base on information about 382 Holstein cows from the Antioquia province. 1345 lac-tations were taken for the association analysis with milk production and 293 lactations were taken for fat and protein percentages and for a somatic cells count (SCC). The production and the composition of the milk were monitored during, at least, a who-le lactation. The genotyping was performed by the use of the PCR-TfLP technique. results. The allelic frequencies were 0.78 and 0.22 for A and b, respec-tively. The genotypic frequencies were 0.60, 0.36 and 0.04 for AA, Ab y bb, respectively. There were significant differences (P<0.05) between the measu-rements of protein percentages and SCC between the three genotypes. for the protein percentage, the BB genotype had 0.18% of superiority and for SCC the AB genotype showed a reduction of 0.77 in such rate. for the other characteristics, no significant di-fferences were found. conclusions. These results suggest that the LTf bovine gene is a good indicator of the susceptibility or the resistance to subclinical mastitis and is associated to the protein percentage in the milk.esAcceso abiertoCorporación Universitaria LasallistaMarcadores molecularesMejoramiento genéticoProducción de lecheinfo:eu-repo/semantics/openAcces